Mrs. Ed - From the 2002 Calendar

Of concern with any woman taking estrogen supplements is the prospect of increased rates of breast cancer.  As this cartoon went into print, the massive estrogen study hoping to demonstrate health improvement among women was abruptly stopped -- when increased breast cancer rates were noted.  Couple that with the lamentable conditions of the perpetually-pregnant horses who serve as the source for many of those estrogens and well, this sketch seemed more prescient than sarcastic... Ah well...